5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID

5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID - Names and Identifiers

Name	5-Bromo-2-fluoropyridine-3-boronic acid
Synonyms	5-Bromo-2-Fluoropyridine-3-Bor 5-BROMO-2-FLUOROPYRIDIE-3-BORONIC ACID 5-Bromo-2-fluoro-3-pyridylboronic acid 2-Fluoro-5-Bromopyridine-3-Boronic Acid 5-Bromo-2-fluoropyridine-3-boronic acid 5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID 5-BROMO-2-FLUOROPYRIDINE-3-BORONIC ACID 5-BROMO-2-FLUOROPYRIDIN-3-YLBORONIC ACID (5-bromo-2-fluoropyridin-3-yl)boronic acid (5-BROMO-2-FLUORO-3-PYRIDINYL)-BORONIC ACID 5-bromo-2-fluoropyridin-3-yl-3-boronic acid
CAS	501435-91-2
EINECS	000-000-0
InChI	InChI=1/C5H4BBrFNO2/c7-3-1-4(6(10)11)5(8)9-2-3/h1-2,10-11H

5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID - Physico-chemical Properties

Molecular Formula	C5H4BBrFNO2
Molar Mass	219.8
Density	1.86±0.1 g/cm3(Predicted)
Melting Point	>300°C
Boling Point	357.1±52.0 °C(Predicted)
Flash Point	169.7°C
Vapor Presure	1.02E-05mmHg at 25°C
Appearance	Crystalline powder
pKa	5.70±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.574
MDL	MFCD04039317

5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
Hazard Class	IRRITANT

5-BROMO-2-FLUORO-3-PYRIDINEBORONIC ACID - Introduction

Acid is an organic compound with a chemical formula of C5H4BBrFN and a molecular weight of 187.9g/mol. The following is a specific description of its nature, use, preparation and safety information:

Nature:
-Appearance: Light yellow to white solid
-melting point: about 150-155 ℃
-Solubility: can be dissolved in most organic solvents, slightly soluble in water
-Molecular structure: This compound contains bromine, fluorine and boron atoms and is a reactant for aldehyde condensation reaction

Use:
-must acid can be used as reagents and intermediates in organic synthesis.
-It is often used in the field of coordination chemistry and pharmaceutical research.

Preparation Method:
The preparation method of acid is as follows:
1. First, 2-fluoropyridine is prepared in an anhydrous system, usually by reacting fluorochloroalkane with pyridine.
2. React the prepared 2-fluoropyridine with bromo boric acid to obtain acid.

Safety Information:
The safety information of acid is limited, so the following matters should be paid attention to during operation and storage:
-Avoid contact with strong oxidants.
-Follow laboratory safety procedures during operation and wear appropriate personal protective equipment, such as gloves and goggles.
-Store in a cool, dry, well-ventilated place, away from fire and heat sources.
-Avoid inhalation, ingestion or contact with skin and eyes. If contact occurs, immediately flush the affected area with plenty of water and seek medical attention.

Last Update：2024-04-09 21:01:54